{"id":25432,"date":"2026-04-08T08:56:42","date_gmt":"2026-04-08T08:56:42","guid":{"rendered":"https:\/\/www.oxypharm.net\/?p=25432"},"modified":"2026-04-08T08:56:42","modified_gmt":"2026-04-08T08:56:42","slug":"pharmaceutical-contamination-control-oxypharm-protocol","status":"publish","type":"post","link":"https:\/\/www.oxypharm.net\/en\/pharmaceutical-contamination-control-oxypharm-protocol\/","title":{"rendered":"The pharmaceutical sector: controlling contamination risk with the power of a comprehensive protocol developed by Oxy\u2019Pharm"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_single_image image=&#8221;25404&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221; el_class=&#8221;full-width&#8221;][vc_column_text css=&#8221;&#8221;]<\/p>\n<h3>Environmental safety: an integrated approach for absolute control over environmental contamination<\/h3>\n<p>[\/vc_column_text][vc_column_text css=&#8221;&#8221;]In the pharmaceutical industry, contamination control is not optional \u2013 it is an absolute imperative. To meet the stringent demands of the most sensitive environments, Oxy\u2019Pharm offers a unique combination of certified solutions and technologies, designed to ensure microbiological safety at every stage of the process.<\/p>\n<p>&nbsp;<\/p>\n<p>Cleaning, detergent application and automated bio-disinfection: all these steps are covered by a comprehensive, field-proven, and environmentally responsible protocol.[\/vc_column_text][vc_column_text css=&#8221;&#8221;]<\/p>\n<h3 class=\"H2\" style=\"line-height: 115%;\">Critical areas, protocols and imperatives: the challenges of microbiological control in pharmaceutical environments<\/h3>\n<p>[\/vc_column_text][vc_column_text css=&#8221;&#8221;]In the pharmaceutical sector, all working environments laboratories, production units, packaging rooms, and cleanrooms are subject to extremely strict contamination control regulations. Every space, every piece of equipment, every surface is a critical link in the manufacturing chain. A residue, an uncleaned surface, or airborne contamination can compromise the integrity of an entire batch and expose the laboratory to major non-conformities.<\/p>\n<p>&nbsp;<\/p>\n<p>To prevent any microbiological, particulate, or chemical risk, Good Manufacturing Practice (GMP) guidelines require rigorous, validated cleaning and disinfection protocols adapted to each risk zone.<\/p>\n<p>&nbsp;<\/p>\n<p>Areas are classified according to their microbiological critical status. This classification determines required air cleanliness levels, particle control, and airflow management. Zones A and B are the most critical, particularly for aseptic operations. They require HEPA-filtered air, thorough surface disinfection, and tight control of airborne contamination.<\/p>\n<p>&nbsp;<\/p>\n<p>Furthermore, cleaning and disinfection protocols must be validated, documented, and reproducible:<\/p>\n<ul>\n<li>Each step (cleaning, rinsing, disinfection) must be formally validated.<\/li>\n<li>Efficacy must be demonstrated against relevant pathogens (bacteria, spores, viruses).<\/li>\n<li>Every operation must be traceable, with written instructions and trained personnel.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>Particular attention must be paid to sensitive equipment and materials:<\/p>\n<ul>\n<li>Electronic or moisture-sensitive devices must be protected by non-corrosive, residue-free methods.<\/li>\n<li>Equipment materials must resist the disinfectants used, without corrosion or degradation.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>To meet these requirements, Oxy\u2019Pharm deploys a comprehensive, coherent approach designed to secure the entire hygiene chain: \u2022 Cleanrooms: steam bio-cleaning (Sanivap) + automated, residue-free disinfection (Nocotech) to preserve controlled atmosphere and HEPA\/ULPA filters.<\/p>\n<ul>\n<li>Transfer areas, safety cabinets and airlocks: controlled airflows and prevention of cross-contamination through automated, reproducible cycles using the Nocotech range.<\/li>\n<li>Tanks, mixers, and benches: effective bio-cleaning of biofilms and organic soiling using high-temperature Sanivap steam.<\/li>\n<li>Furniture, partitions, floors and electronic equipment: non-corrosive, no-rinse, non-altering treatment via the Sanivap\/Nocotech protocol.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>By combining high-temperature steam and airborne disinfection technologies, Oxy\u2019Pharm provides an integrated 2-in-1 protocol, adaptable to various critical status levels, ensuring safety, regulatory compliance, and ease of use.[\/vc_column_text][vc_column_text css=&#8221;&#8221;]<\/p>\n<h3>A bespoke solution : the power of a 2-in-1 Oxy\u2019Pharm protocol<\/h3>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row content_placement=&#8221;middle&#8221;][vc_column width=&#8221;2\/3&#8243;][vc_column_text css=&#8221;&#8221;]<\/p>\n<h4>SANIVAP : THE STEAM SOLUTION FOR RESIDUE-FREE CLEANING AND DISINFECTION \u2013 WHETHER WITH OR WITHOUT CHEMICALS<\/h4>\n<p>[\/vc_column_text][vc_column_text css=&#8221;&#8221;]In environments with the highest microbiological requirements, high-temperature steam offers an effective, safe, and material-friendly solution. Sanivap, Oxy\u2019Pharm\u2019s steam bio-cleaning solution, combines performance, simplicity, and sustainability to meet pharmaceutical cleanliness standards.<\/p>\n<p>&nbsp;<\/p>\n<p>This technology relies on the release of saturated steam at 97 \u00b0C at the outlet. This controlled heat eliminates soiling, biofilms, and pathogens (bacteria, viruses, yeasts, spores) without chemicals. The result is residue-free, no-rinse disinfection that does not damage materials \u2013 a key benefit in production, packaging, and laboratory areas where every surface matters.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;707&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=&#8221;&#8221;]Certified under NF T72-110, Sanivap is ideally suited to pharmaceutical environments.<\/p>\n<p>Designed for intensive use, it operates autonomously for up to 10 hours and adapts to every surface with a wide range of accessories \u2013 textile brushes, sanitary nozzles, disinfection hoods, steam mops, and more. Mounted on an ergonomic trolley, it simplifies daily operations while ensuring a high level of safety and reproducibility.[\/vc_column_text][vc_column_text css=&#8221;&#8221;]<\/p>\n<h4>NOCOTECH : AUTOMATED, CONTACT-FREE, AIRBORNE DISINFECTION THAT LEAVES NO RESIDUE<\/h4>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row content_placement=&#8221;middle&#8221;][vc_column width=&#8221;1\/4&#8243;][vc_single_image image=&#8221;25411&#8243; img_size=&#8221;Full&#8221; alignment=&#8221;center&#8221; css=&#8221;&#8221;][\/vc_column][vc_column width=&#8221;3\/4&#8243;][vc_column_text css=&#8221;&#8221;]In critical pharmaceutical environments, even the smallest untreated surface can compromise batch integrity, pose health risks, or cause costly non-compliance. To address these challenges, Oxy\u2019Pharm has developed the Nocotech range: an automated, contact-free airborne bio-disinfection solution, now used by laboratories and production sites worldwide. Based on hydrogen peroxide (H\u2082O\u2082), this environmentally responsible technology ensures effective disinfection while protecting the environment \u2014 after use, it naturally decomposes into harmless water and oxygen. At its core are two complementary devices: Nocospray and Nocospray Kube.[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=&#8221;&#8221;]<\/p>\n<ul>\n<li>Nocospray (5.9 kg): mobile and easy to programme, it releases a dry mist at 80 m\/s with particles under 5 \u00b5m, ensuring homogeneous diffusion in spaces from 10 m\u00b3 to 1 000 m\u00b3, even into hard-to-reach areas. No manual contact, no post-treatment handling (beyond initial cleaning): disinfection is fast, reliable, and simple. It can be used with bio-disinfectants, enabling effective, residue-free treatment that respects surfaces.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>Nocospray Kube: designed specifically for small spaces (1\u201310 m\u00b3), such as biological safety cabinets, transfer hatches or isolators. Ultra-lightweight (3.1 kg) and battery-powered, it offers excellent portability. Its vibrating-membrane technology produces a uniform, dry mist without residual humidity, protecting even the most sensitive or electronic surfaces.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>Intuitive and programmable via a touchscreen, Nocospray Kube allows precise adjustment of the programmed space to be treated, dosage, contact time, and number of cycles. Detailed, exportable usage reports support documentation within qualified protocols, guaranteeing both safety and efficiency.<\/p>\n<p>&nbsp;<\/p>\n<p>Both devices use Nocolyse (6% H\u2082O\u2082 + silver) and Nocolyse One Shot (12% H\u2082O\u2082) bio-disinfectants.<\/p>\n<p>Under pharmaceutical GMP, disinfectant efficacy is validated through a qualified protocol achieving a 6-log reduction on biological indicators such as Geobacillus stearothermophilus the reference standard for contamination control. Nocolyse 12% is the standard concentration for qualification and routine use, while Nocolyse 6% is suitable for specific cases requiring lower concentration, albeit under stricter validation.<\/p>\n<p>&nbsp;<\/p>\n<p>Both formulations are biodegradable, non-corrosive, non-allergenic, and leave no residue \u2013 a vital feature for sensitive areas such as cleanrooms, aseptic filling zones, and QC laboratories. They are fully compatible with all common materials (stainless steel, glass, plastic, electronics) without alteration or humidity.<\/p>\n<p>&nbsp;<\/p>\n<p>Certified to EN 17272, this technology ensures full efficacy against bacteria, yeasts, viruses, fungi, and mycobacteria, including sporicidal activity meeting GMP contamination control standards and the high demands of the pharmaceutical industry.<\/p>\n<p>Remotely programmable and easily integrated into documented protocols, Nocotech is an essential component of a robust pharmaceutical quality system.[\/vc_column_text][vc_column_text css=&#8221;&#8221;]<\/p>\n<h3 class=\"H2\" style=\"line-height: 115%;\">Covering all surfaces, all uses, and all risks<\/h3>\n<p>[\/vc_column_text][vc_column_text css=&#8221;&#8221;]Oxy\u2019Pharm provides an integrated solution capable of effectively treating all critical points of a pharmaceutical site \u2014 without compromising safety, efficacy, or material compatibility :<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>\u00a0Large or vertical surfaces (floors, partitions, glass, stainless steel furniture): Sanivap steam cleaning and Nocotech DSVA ensure full coverage without residues or surface alteration.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>Ambient air and inaccessible areas : Nocospray bio-disinfection covers all surfaces in a single operation, achieving uniform coverage even in complex spaces.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>Tanks, mixers, benches, fume hoods: Sanivap\u2019s specialised accessories (mops, nozzles, brushes) allow targeted cleaning, even in technical or congested areas.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>With no rinsing, no residue, and minimal maintenance, Oxy\u2019Pharm\u2019s solutions integrate easily into existing protocols and comply with the strictest validation standards of the pharmaceutical industry \u2013 a certified, modular approach covering 100% of contamination risks.[\/vc_column_text][vc_column_text css=&#8221;&#8221;]<\/p>\n<h3>Proven effectiveness and a validated, certified approach<\/h3>\n<p>[\/vc_column_text][vc_column_text css=&#8221;&#8221;]In a sector as regulated and audited as pharmaceuticals, hygiene protocols must be objective, traceable, reproducible, and certified. Oxy\u2019Pharm solutions fully meet these criteria, combining scientific validation, user safety, and regulatory compliance.<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>Sanivap steam bio-cleaning devices are certified Class IIa Medical Devices (GMED 0459), validated under NF T72-110, ensuring full action against bacteria, spores, yeasts, viruses, and fungi. Sanivap effectiveness is guaranteed thanks to the constant steam temperature at the accessory outlet \u2013 even after several hours of use. This ensures reliable, reproducible disinfection throughout all protocols.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>Nocotech surface bio-disinfection technology is certified EN 17272, the European benchmark for automated disinfection systems, proven effective even under real-world conditions \u2013 including in sporicidal protocols. This guarantees the high level of control over critical micro-organisms, and meets the strict contamination criteria imposed by industry GMP.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<ul>\n<li>Safe formulations : peracetic-acid-free, biodegradable, non-corrosive, non-allergenic, and residue-free \u2013 ensuring full compatibility with ultra-controlled environments and sensitive equipment. \u2022 With Oxy\u2019Pharm, pharmaceutical and biotechnology companies benefit from a proven, safe, and certified approach, easily integrated into Quality, QHSE, and regulatory validation systems.<\/li>\n<\/ul>\n<p>[\/vc_column_text][vc_column_text css=&#8221;&#8221;]<\/p>\n<h3>Tangible operational advantages for your teams<\/h3>\n<p>[\/vc_column_text][vc_column_text css=&#8221;&#8221;]Beyond microbiological performance, Oxy\u2019Pharm solutions offer major operational advantages for hygiene and production teams. Designed for real-world use, they enhance both procedural quality and working conditions.<\/p>\n<p>&nbsp;<\/p>\n<ul>\n<li>Reduced occupational risks: steam and Nocotech technologies drastically reduce exposure to chemicals. The ergonomic design of Sanivap and automation of Nocotech cycles prevent musculoskeletal strain by reducing repetitive manual handling.<\/li>\n<li>Time efficiency: Sanivap\u2019s one-pass cleaning power and Nocospray\u2019s contact-free disinfection accelerate turnover while maintaining consistent quality<\/li>\n<li>Optimised organisation : Nocotech devices are programmable and adaptable, improving scheduling, reproducibility, and quality assurance responsiveness.<\/li>\n<li>Eco-responsibility: minimal detergent use and no rinsing reduce water and chemical consumption, supporting sustainability goals.<\/li>\n<li>Ease of use and training : intuitive equipment, compact formats, simple interfaces, and specialised accessories. Oxy\u2019Pharm provides full training, validation support, and technical assistance tailored to pharmaceutical environments.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>Safer, simpler, faster protocols \u2013 that is Oxy\u2019Pharm\u2019s promise to enhance collective performance without compromising quality.[\/vc_column_text][vc_column_text css=&#8221;&#8221;]<\/p>\n<h3>An integrated solution for long-term, certified microbiological control<\/h3>\n<p>[\/vc_column_text][vc_column_text css=&#8221;&#8221;]In a sector where the slightest lapse can jeopardise months of production, Oxy\u2019Pharm stands out as a trusted partner for pharmaceutical professionals. By combining two complementary technologies Sanivap for steam bio-cleaning and Nocotech for airborne bio-disinfection Oxy\u2019Pharm delivers coherent hygiene protocols that meet the highest regulatory standards.<\/p>\n<p>&nbsp;<\/p>\n<p>Discover our dedicated pharmaceutical industry brochure, or contact our teams for tailored support.[\/vc_column_text][vc_column_text css=&#8221;&#8221;]<\/p>\n<h3>Feedback from Tecsoin : a Colombian distributor of the Nocotech solution<\/h3>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row content_placement=&#8221;middle&#8221;][vc_column width=&#8221;2\/3&#8243;][vc_column_text css=&#8221;&#8221;]Tecsoin is a Colombian distributor specialising in high-value industrial solutions. Representing internationally recognised brands, Tecsoin supports pharmaceutical, food, cosmetics, chemical, and biotechnology sectors with tailor-made solutions that meet the strictest hygiene, safety, and industrial performance requirements.<\/p>\n<p>&nbsp;<\/p>\n<p>The company successfully distributes Oxy\u2019Pharm\u2019s Nocotech technology across Colombian pharmaceutical laboratories, helping to implement reliable, automated, and compliant hygiene protocols. In 2020, at the height of the Covid-19 pandemic, Tecsoin was looking for a disinfection technology that was effective, reliable, and suitable for critical environments. This led it to discover Oxy\u2019Pharm\u2019s Nocotech a strategic turning point for its pharmaceutical operations.[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/3&#8243;][vc_single_image image=&#8221;25421&#8243; img_size=&#8221;full&#8221; css=&#8221;&#8221;][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text css=&#8221;&#8221;]Since then, Nocotech solutions have been widely adopted across Colombia\u2019s most demanding pharmaceutical laboratories, including those producing sterile and ophthalmic products.<\/p>\n<p>&nbsp;<\/p>\n<p>Tecsoin deploys the full Nocolyse disinfectant range with Nocospray diffusers to deliver contact-free aerial bio-disinfection (DSVA). What appeals to Colombian users ? Demonstrable efficacy. \u201cDuring demonstrations, our partners are impressed by the clear reduction in microbiological load. Nocotech\u2019s dry mist reaches every corner \u2014 something traditional methods cannot achieve.\u201d<\/p>\n<p>&nbsp;<\/p>\n<p>Reduced operational costs are another key advantage: lower consumable use, fewer staff required (one operator can run the cycle), and time savings in disinfection procedures.<\/p>\n<p>\u201cIt allows them to standardise disinfection procedures with exemplary rigour while complying with GMP.\u201d<\/p>\n<p>&nbsp;<\/p>\n<p>A clear indicator of success: major pharmaceutical company Vitalis multiplied its equipment in just a few months from one diffuser to six. Around 40 Nocotech devices are now sold annually, a steadily rising figure reflecting growing demand for advanced bio-disinfection technologies.<\/p>\n<p>&nbsp;<\/p>\n<p>Tecsoin also values Oxy\u2019Pharm\u2019s expert support in training and implementation:<\/p>\n<p>\u201cOur engineers are trained to demonstrate and teach other users. The technology is easy to handle, but we also ensure personalised support.\u201d<\/p>\n<p>&nbsp;<\/p>\n<p>Today, Tecsoin is expanding into the food industry and initiating regulatory processes to introduce Nocotech DSVA and Sanivap steam technologies into the healthcare sector. This is an ambitious growth path and one driven by the proven performance of Oxy\u2019Pharm solutions.[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>In the pharmaceutical industry, contamination control is critical. Oxy\u2019Pharm delivers a global protocol combining Sanivap steam bio-cleaning and automated Nocotech bio-disinfection to secure the most sensitive environments.<\/p>\n","protected":false},"author":3,"featured_media":25406,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[55],"tags":[291,307,87,308,309,310,227,311,202,292,312,293],"class_list":["post-25432","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles-en","tag-dsva-en","tag-industrie-pharmaceutique-en","tag-nocotech-en","tag-normes-en","tag-performance-en","tag-pharma-en","tag-sanivap-en","tag-sans-residus-en","tag-securite-en","tag-securite-sanitaire-en","tag-tms-en","tag-vapeur-en"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.1.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The pharmaceutical sector: controlling contamination risk with the power of a comprehensive protocol developed by Oxy\u2019Pharm - 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